The PubMed Related Citations algorithm returns a scored and ranked list of the 20 most relevant citations in HTML format similar to the following sample:
<HTML>
<HEAD>
<TITLE>neighbouring</TITLE>
</HEAD>
<BODY bgcolor="ffffff">
<br><pre><b>The neighbours are:</b></pre><hr>
(1)
97.027 Rosenbaum JL, Almli CR, Yundt KD, Altman DI, Powers WJ<br>
<A href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9339686">9339686</A>
Higher neonatal cerebral blood flow correlates with worse childhood neurologic outcome.<hr>
(2)
33.9859 Altman DI, Powers WJ, Perlman JM, Herscovitch P, Volpe SL, Volpe JJ<br>
<A href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3263081">3263081</A>
Cerebral blood flow requirement for brain viability in newborn infants is lower than in adults.<hr>
...
(20)
24.6715 Bednarczyk EM, Rutherford WF, Leisure GP, Munger MA, Panacek EA, Miraldi FD, Green JA<br>
<A href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2343589">2343589</A>
Once we have this data, we do the following for each of the 20 relevant citations returned:
- Parse the output to find the score and reference UID for each of the 20 citations.
- Call the NCBI Text Tool Server for each of the 20 relevant citation UIDs. This retrieves the citation from PubMed in MEDLINE format which allows us to then parse out the MeSH Headings (lines with "MH -"). The output looks similar to the following sample:
UI - 97479605
PMID- 9339686
DA - 19971114
DCOM- 19971114
LR - 20001218
IS - 0028-3878
VI - 49
IP - 4
DP - 1997 Oct
TI - Higher neonatal cerebral blood flow correlates with worse childhood
neurologic outcome.
PG - 1035-41
AB - Cerebral blood flow (CBF) in newborn infants is often below levels
necessary to sustain brain viability in adults. Controversy exists
regarding the effects of such low CBF on subsequent neurologic function.
We determined the current childhood neurologic status and IQ in 26
subjects who had measurements of CBF performed with PET in the neonatal
period between 1983 and 1989 as part of a study of hypoxic-ischemic
encephalopathy. Follow-up information at ages 4 to 12 years was obtained
on all 26 subjects. Ten subjects had died. All 16 survivors underwent
clinical neurologic evaluation, and 14 also underwent intelligence
testing. Eight had abnormal clinical neurologic evaluations; eight were
normal. The mean neonatal CBF in those with abnormal childhood neurologic
outcome was significantly higher than in those with normal childhood
neurologic outcome (35.64 +/- 11.80 versus 18.26 +/- 8.62 mL 100 g(-1)
min(-1), t = 3.36, p = 0.005). A significant negative correlation between
neonatal CBF and childhood IQ was demonstrated (Spearman rank correlation
r = -0.675, p = 0.008). Higher CBF was associated with lower IQ. The
higher CBF in subjects with worse neurologic and intellectual outcome may
reflect greater loss of cerebrovascular autoregulation or other vascular
regulatory mechanisms due to more severe brain damage.
AD - Department of Pediatrics, Washington University School of Medicine, St.
Louis Children's Hospital, MO 63110, USA.
AU - Rosenbaum JL
AU - Almli CR
AU - Yundt KD
AU - Altman DI
AU - Powers WJ
LA - eng
ID - NS06833/NS/NINDS
ID - NS32568/NS/NINDS
PT - Journal Article
CY - UNITED STATES
TA - Neurology
JC - NZ0
JID - 0401060
SB - AIM
SB - IM
MH - Cerebrovascular Circulation/*physiology
MH - *Child Development
MH - Follow-Up Studies
MH - Human
MH - Infant, Newborn
MH - Intelligence
MH - *Nervous System Physiology
MH - Neurologic Examination
MH - Support, Non-U.S. Gov't
MH - Support, U.S. Gov't, P.H.S.
MH - Tomography, Emission-Computed
EDAT- 1997/10/27 20:29
MHDA- 1997/10/27 20:29
PST - ppublish
SO - Neurology 1997 Oct;49(4):1035-41.
Once we have the citation from PubMed, we need to do the following:
- Pull the MeSH Heading ("MH - ") lines from the citation.
- Track whether the MeSH Heading is an IM term or not.
- Combine the MH with the appropriate UI and original score from the relevant citation we are working on.
- The final output of this process is a scored and ranked list of all MeSH Headings from the 20 relevant citations with a line of "***" separating each of the relevant citation's MeSH Headings. The output would look similar to the following:
97479605|IM|Brain|33.9859
97479605|IM|Brain Diseases|33.9859
97479605|IM|Cerebrovascular Circulation|33.9859
97479605|NIM|Gestational Age|33.9859
97479605|NIM|Infant, Premature|33.9859
97479605|IM|Tomography, Emission-Computed|33.9859
***
97479605|NIM|Asphyxia Neonatorum|29.0115
97479605|IM|Brain|29.0115
97479605|IM|Brain Ischemia|29.0115
97479605|IM|Cerebrovascular Circulation|29.0115
97479605|IM|Hypoxia, Brain|29.0115
97479605|IM|Intracranial Pressure|29.0115
97479605|IM|Oxygen|29.0115
97479605|NIM|Prognosis|29.0115
***
...
***
97479605|IM|Cerebrovascular Circulation|24.6715
97479605|NIM|Hypercapnia|24.6715
97479605|IM|Hyperventilation|24.6715
97479605|NIM|Oxygen Radioisotopes|24.6715
97479605|NIM|Tomography, Emission-Computed|24.6715 ***
